Use Of Cannabis, marijuana, hemp?
When it comes to “weed”, it often tends to get confusing. Plant native to Central Asia, cannabis , also known as hemp , produces real Marijuana thanks to its dried female inflorescences. In nature there are different varieties of hemp containing in varying proportions different psychoactive substances, narcotic and non-narcotic.
The main active ingredient that causes changes in the brain is THC (delta-9-tetrahydrocannabinol) contained in the golden resin released by the inflorescences of the plant. Among the 60 cannabinoids present in Cannabis, in addition to CDB or also called Cannabidiol, THC is the principle present in greater quantities.
It is able to bind, once taken and in a very specific way, to receptors present on the surface of the cells present in our organism called CB1 and CB2. These receptors allow the substance to reach the spine, lungs, kidneys, brain, central nervous system and immune system.
The benefits of cannabinoids
Today there are several debates on the use of cannabis: can it become a fundamental medical aid or a gateway that leads to the abuse of this substance? Two positions in stark contrast.
There is no doubt, however, that THC and CDB have many therapeutic benefits and a pharmacological efficacy now proven by universally shared studies.
In fact, if used responsibly, cannabinoids become effective methods to soothe the symptoms of various diseases.
While tetrahydrocannabinol, responsible for the psychoactive effects of cannabis, has pain-relieving, anti-blood, and appetite-stimulating effects, cannabidiol has analgesic, anti-epileptic, antipsychotic and anxiolytic effects.
When can medical cannabis be useful?
The pathologies on which the administration of cannabinoids has reported great improvements are many. In pain therapy ( neuropathic and oncological) in which treatment with opiates, cortisone drugs and non-steroidal anti-inflammatory drugs has proved ineffective, THC has become a viable solution to relieve pain.
In fact, several studies have shown that THC is able to block pain signals that reach the brain thanks to their ability to alter the central nervous system.
The analgesic Use Of Cannabis also helps relieve pain in individuals with multiple sclerosis or spinal cord injuries thanks to the potential of THC to block the breakdown of neural connections that lead to worsening of the disease.
The Use Of Cannabis intake in subjects suffering from anorexia, cachexia, cancer patients and AIDS patients are also evident. The drug allowed them to improve
Cannabis also plays a key role in the treatment of nausea and vomiting caused by chemotherapy.
As Paolo Poli, president of Sirca explains, cannabis is useful in all those pathologies that can affect the central nervous system such as ALS and Parkinson’s.
Cannabidiol, according to a study conducted by Philiph McGuire, a London-based clinical researcher, could be effective on patients suffering from psychosis.
In his study, a group of schizophrenic patients treated with CBD found improvements in cognitive performance compared to patients treated with placebo drugs.
Finally, a clinical study conducted at the medical school of Hanover has shown that treatment with cannabinoids improves the symptoms of all those patients suffering from ST or also called Tourette’s Syndrome.
Contraindications: not recommended for young people and adolescents , more prone to mental alterations, for those suffering from cardio-pulmonary disorders, renal or hepatic insufficiency, for those suffering from mental disorders or familiar with schizophrenia.
Furthermore, if you are already taking drugs with sedative, antidepressant or psychoactive effects, cannabis is not recommended because it could aggravate the effects.
Finally, it is forbidden for women planning a pregnancy, pregnant or breastfeeding. It is also likely that it will test positive for doping tests and the controls required by the highway code.
Who can access therapeutic cannabis?
Cannabis can be prescribed, with responsibility and compliance with current regulations, in all those patients suffering from the aforementioned diseases.
The drug can also be prescribed in cases of postoperative pain, lupus erythematosus , chronic inflammatory bowel diseases such as Crohn’s disease , psoriasis , fibromyalgia and low back pain , post traumatic stress disorder caused by a particular type of memory that tends to revive, glaucoma , sleep disorders and Alzheimer’s patients .
Methods of intake and dosage of medical cannabis
The intake of cannabinoids present in the plant can be carried out by vaporization, topically, by inhalation or orally. The choice depends on the pharmaceutical formulation and the desired effect.
In any case, in order for the substances present in the plant to be activated, they must undergo a chemical process called “decarboxylation”, that is a chemical reaction that involves the molecules and in which the latter are brought to a temperature of over 100 degrees centigrade.
As for the dosage for therapeutic use, the amount varies from person to person. The dosage must necessarily be established by the doctor and varies from a minimum of 1 gram to a maximum of 5 grams per day.